: The progress of biomedical sciences depends on the availability of advanced instrumentation and imaging tools capable of attaining the state of biological systems in vivo without using exogenous markers. Mechanical forces and local elasticity play a central role in understanding physical interactions in all living systems. We demonstrate a novel way to image microscopic viscoelastic properties of biological systems using Brillouin microspectroscopy [1]. In my talk, I will discuss the ways how an old spectroscopic tool can be used for real time microscopic imaging [2-3] and provide possible solutions to long standing problems in Life Sciences and Medicine [4-6].
References:
[1] Zh. Meng, et al., Advances in Optics and Photonics 8(2), 300-327 (2016).
[2] Zh. Meng, et al., Journal of Biophotonics 9(3), 201-207 (2016).
[3] C. W. Ballmann, et al., Optica 4(1), 124-128 (2017).
[4] Zh. Meng, et al., ACS Nano 11(8), 7690–7696 (2017).
[5] M. Troyanova-Wood, et al., Biomedical Optics Express 10(4), 1774-1781 (2019).
[6] D. Akilbekova, et al., Journal of Biomedical Optics 23(9), 097004 (2018).
Dr. Vladislav V. Yakovlev is a full professor in the Departments of Biomedical Engineering, Electrical and Computer Engineering and Physics & Astronomy at Texas A&M University. He got his PhD in 1990 from Moscow State University. After a short stay with Novatec Laser System, Inc., where he discovered what is now known as bladeless LASIK, he worked in the Department of Chemistry and Biochemistry at UCSD as a postdoctoral researcher and research scientist developing new tools for optical molecular spectroscopy, imaging and control. Dr. Yakovlev started as an assistant professor at the University of Wisconsin – Milwaukee in 1998 and moved to Texas A&M University in 2011. He has more than 150 research publications in leading scientific journals. His research was supported by NSF, NIH, ARO, AFOSR, ONR, and DARPA. Dr. Yakovlev is a Fellow of OSA, AIMBE, APS and SPIE. He is a member of Editorial Board of Journal of Biomedical Optics, Optica and Applied Sciences. His research interests are in a broad area of optical spectroscopy, microscopy, imaging and sensing.